Lithium and thyrotoxicosis.

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چکیده

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Thyrotoxicosis Followed by Hypothyroidism in a Patient on Lithium

While hypothyroidism is common in lithium-treated patients, thyrotoxicosis is rarely reported. We present a female patient on lithium for maintenance therapy of bipolar affective disorder, who developed thyrotoxicosis for few months which was followed by hypothyroidism which continued. There was no further thyrotoxicosis episode during a five year follow up period. While she was treated for thy...

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Lithium as an Alternative Option in Graves Thyrotoxicosis

A 67-year-old woman was admitted with signs and symptoms of Graves thyrotoxicosis. Biochemistry results were as follows: TSH was undetectable; FT4 was >6.99 ng/dL (0.7-1.8); FT3 was 18 pg/mL (3-5); TSI was 658% (0-139). Thyroid uptake and scan showed diffusely increased tracer uptake in the thyroid gland. The patient was started on methimazole 40 mg BID, but her LFTs elevated precipitously with...

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Use of lithium in the treatment of thyrotoxicosis.

OBJECTIVES To evaluate the efficacy and safety of lithium in the treatment of thyrotoxicosis, and to study the dose and serum levels at which therapeutic response occurs. DESIGN Retrospective study. SETTING Thyroid clinic of a regional hospital in Hong Kong. PATIENTS Thirteen patients with thyrotoxicosis pending therapy with radioiodine or surgery, in whom thionamides were contra-indicate...

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The use of lithium in the treatment of thyrotoxicosis.

Since lithium has been shown to inhibit release of iodine from the thyroid, we have investigated its therapeutic potential in thyrotoxicosis. Eight detailed (131)I kinetic studies were performed on seven thyrotoxic women and data was analyzed using a computer program. Lithium at serum levels of about 1 mEq liter decreased the loss of (131)I from the thyroid, led to a fall in serum (131)I levels...

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Thyrotoxicosis

" Scire est nescire, nisi id me Scire alius sciret SPRING, 194:1. It would not be possible to deal at all fully with the scientific aspects of this subject in an article of reasonable length, and still less would it be possible to give a resume of the enormous literature that has grown up concerning it. My purpose is much simpler ; it is to present a record of personal experience and to offer s...

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ژورنال

عنوان ژورنال: BMJ

سال: 1977

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.6089.765-a